Spain's red wines an has an abundance of native grape varieties, with over 400 varieties planted throughout Spain though 88 percent of the country's wine production is from only 20 grapes — including the reds Tempranillo, Bobal, Garnacha, and Monastrell.

The red wine grape Tempranillo is the second most widely planted grape variety.It is known throughout Spain under a variety of synonyms that may appear on Spanish wine labels including Cencibel, Tinto Fino and Ull de Llebre.

Both Tempranillo and Garnacha are used to make the full-bodied red wines associated with the Rioja, Ribera del Duero and Penedès with Garnacha being the main grape of the Priorat region. In the Levante region, Monastrell and Bobal have significant plantings, being used for both dark red wines and dry rosé.

As the Spanish wine industry becomes more modern, there has been a larger presence of international grape varieties appearing in both blends and varietal forms, most notably Cabernet Sauvignon, Chardonnay, Syrah, Merlot and Sauvignon blanc. Other Spanish grape varieties that have significant plantings include Cayetana Blanca and Mencía.